Dr. Rudolph Tanzi is the Director of the Genetics and Aging Research Unit, Co-Director of the McCance Center for Brain Health, Co-Director of the MassGeneral Institute for Neurodegenerative Disease, and Vice-Chair of Neurology at Massachusetts General Hospital. He is also the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi is a co-founder of the Cure Alzheimer’s Fund, for which he serves as the Chair of the Research Leadership Group. Dr. Tanzi co-discovered the first Alzheimer’s disease (AD) genes including the amyloid gene (APP), the presenilin genes, and the first AD neuroinflammation gene, CD33. He also discovered the Wilson’s disease gene and other neurological disease genes. Dr. Tanzi’s lab first used human stem cells to create the first human brain organoid models of AD, which have made drug discovery exponentially faster and cheaper. He has used these models to develop novel AD drugs including gamma secretase modulators that lower amyloid production and are being prepared for clinical trials. Dr. Tanzi has helped create numerous biotech companies and published over 725 papers (>165,000citations). He has received numerous awards, including the Metropolitan Life Award, Potamkin Prize, and Smithsonian American Ingenuity Award, is a member of the National Academy of Medicine, and has been included on the list of the TIME100Most Influential People in the World. Dr. Tanzi is also a New York Times bestselling author of Decoding Darkness, Super Brain, Super Genes, and The Healing Self, for which he has hosted several television shows on PBS.